Systems neuroscience research is increasingly possible through the use of integrated molecular and circuit-level analyses. These studies depend on the use of animal models and, in many cases, molecular and circuit-level analyses. Associated with genetic, pharmacologic, epigenetic, and other types of environmental manipulations. We illustrate typical pitfalls resulting from poor validation of behavior tests. We describe experimental designs and enumerate controls needed to improve reproducibility in investigating and reporting of behavioral phenotypes.

中文翻译：

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不良行为：提高行为测试的可重复性

通过使用集成的分子和电路级分析，系统神经科学研究的可能性越来越大。这些研究取决于动物模型的使用，并且在许多情况下取决于分子和电路水平的分析。与遗传，药理，表观遗传和其他类型的环境操作相关。我们说明了行为测试验证不力所导致的典型陷阱。我们描述了实验设计，并列举了改善在调查和报告行为表型中的可重复性所需的控件。