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Super-resolution imaging of lysosomes with a nitroso-caged rhodamine
Chemical Communications ( IF 4.3 ) Pub Date : 2018-01-23 00:00:00 , DOI: 10.1039/c7cc08886h
Haihong He 1, 2, 3, 4, 5 , Zhiwei Ye 6, 7, 8 , Ying Zheng 6, 7, 8 , Xiu Xu 1, 2, 3, 4, 5 , Chunlei Guo 1, 2, 3, 4, 5 , Yi Xiao 6, 7, 8 , Wei Yang 6, 7, 8 , Xuhong Qian 1, 2, 3, 4, 5 , Youjun Yang 1, 2, 3, 4, 5
Affiliation  

Caged-fluorophores are potentially suitable for photo-activated localization microscopy (PALM) for super-resolution imaging. N-Nitroso is a simple and robust photo-cage with biocompatible nitric oxide as the only byproduct upon photolysis. We herein reported a novel PALM probe (NOR535) for super-resolution imaging of lysosomes with high localization precision.

中文翻译:

亚硝基笼中若丹明对溶酶体的超分辨率成像

笼状荧光团可能适合用于超分辨率成像的光激活定位显微镜(PALM)。N-亚硝基是一种简单而坚固的光笼,其生物相容性一氧化氮是光解时唯一的副产物。我们在本文中报道了一种新型的PALM探针(NOR535),用于以高定位精度对溶酶体进行超分辨率成像。
更新日期:2018-03-15
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