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Big Strides in Cellular MicroRNA Expression
Trends in Genetics ( IF 13.6 ) Pub Date : 2018-01-18 , DOI: 10.1016/j.tig.2017.12.015 Marc K. Halushka , Bastian Fromm , Kevin J. Peterson , Matthew N. McCall
中文翻译:
细胞MicroRNA表达大步向前
更新日期:2018-01-18
Trends in Genetics ( IF 13.6 ) Pub Date : 2018-01-18 , DOI: 10.1016/j.tig.2017.12.015 Marc K. Halushka , Bastian Fromm , Kevin J. Peterson , Matthew N. McCall
A lack of knowledge of the cellular origin of miRNAs has greatly confounded functional and biomarkers studies. Recently, three studies characterized miRNA expression patterns across >78 human cell types. These combined data expand our knowledge of miRNA expression localization and confirm that many miRNAs show cell type-specific expression patterns.
中文翻译:
细胞MicroRNA表达大步向前
缺乏对miRNA的细胞起源的了解已大大混淆了功能和生物标记物的研究。最近,三项研究对超过78种人类细胞类型的miRNA表达模式进行了表征。这些组合的数据扩展了我们对miRNA表达定位的了解,并证实了许多miRNA显示出细胞类型特异性表达模式。