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MSH6 and PMS2 germ-line pathogenic variants implicated in Lynch syndrome are associated with breast cancer.
Genetics in Medicine ( IF 6.6 ) Pub Date : 2018-10-01 , DOI: 10.1038/gim.2017.254 Maegan E Roberts 1 , Sarah A Jackson 1 , Lisa R Susswein 1 , Nur Zeinomar 2 , Xinran Ma 2 , Megan L Marshall 1 , Amy R Stettner 1 , Becky Milewski 1 , Zhixiong Xu 1 , Benjamin D Solomon 1 , Mary Beth Terry 2 , Kathleen S Hruska 1 , Rachel T Klein 1 , Wendy K Chung 3
Genetics in Medicine ( IF 6.6 ) Pub Date : 2018-10-01 , DOI: 10.1038/gim.2017.254 Maegan E Roberts 1 , Sarah A Jackson 1 , Lisa R Susswein 1 , Nur Zeinomar 2 , Xinran Ma 2 , Megan L Marshall 1 , Amy R Stettner 1 , Becky Milewski 1 , Zhixiong Xu 1 , Benjamin D Solomon 1 , Mary Beth Terry 2 , Kathleen S Hruska 1 , Rachel T Klein 1 , Wendy K Chung 3
Affiliation
An association of Lynch syndrome (LS) with breast cancer has been long suspected; however, there have been insufficient data to address this question for each of the LS genes individually.
中文翻译：
林奇综合征中涉及的 MSH6 和 PMS2 种系致病变异与乳腺癌相关。
长期以来，人们一直怀疑林奇综合征 (LS) 与乳腺癌存在关联。然而，没有足够的数据来单独解决每个 LS 基因的这个问题。
更新日期：2018-01-19
中文翻译：
林奇综合征中涉及的 MSH6 和 PMS2 种系致病变异与乳腺癌相关。
长期以来，人们一直怀疑林奇综合征 (LS) 与乳腺癌存在关联。然而，没有足够的数据来单独解决每个 LS 基因的这个问题。
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