IgG4-related disease can involve nearly any organ system, including the central and peripheral nervous systems. The pathology findings are consistent from organ to organ, but careful clinicopathological correlation is necessary to establish the diagnosis. Many non-neurological and neurological inflammatory conditions, previously regarded as idiopathic in nature, are now recognised to fall within the spectrum of IgG4-related disease. The condition is highly treatable, but probably remains substantially under-recognised. In this Review, we offer an important and timely update on the current and emerging aspects of this neurological disease. Following a short overview of IgG4-related disease, we describe the current understanding of neurological findings, pathophysiology, approaches to diagnosis, and treatment of IgG4-related disease affecting the central and peripheral nervous systems.

中文翻译：

---

中枢神经系统和周围神经系统的IgG4相关疾病。

IgG4相关疾病几乎可以累及任何器官系统，包括中枢神经系统和周围神经系统。各个器官的病理结果是一致的，但是仔细的临床病理相关性对于确定诊断是必要的。许多非神经性和神经性炎性疾病，以前被认为是特发性的，现在被认为属于IgG4相关疾病的范畴。该病可高度治愈，但可能仍未得到充分认识。在本综述中，我们提供了有关该神经系统疾病当前和新兴方面的重要而及时的更新。在对IgG4相关疾病进行简短概述之后，我们描述了当前对神经系统发现，病理生理学，诊断方法，