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Genomic characterisation of human monkeypox virus in Nigeria
The Lancet Infectious Diseases ( IF 36.4 ) Pub Date : 2018-01-16 , DOI: 10.1016/s1473-3099(18)30043-4
Ousmane Faye 1 , Catherine B Pratt 2 , Martin Faye 1 , Gamou Fall 1 , Joseph A Chitty 3 , Moussa M Diagne 1 , Michael R Wiley 2 , Adesola F Yinka-Ogunleye 4 , Sola Aruna 5 , Ebitimitula N Etebu 6 , Neni Aworabhi 6 , Dimie Ogoina 7 , Wari Numbere 8 , Nwando Mba 4 , Gustavo Palacios 3 , Amadou A Sall 1 , Chikwe Ihekweazu 4
Affiliation  

Monkeypox virus (MPXV) is a large, double-stranded DNA virus belonging to the Orthopox genus in the family Poxviridae. First identified in 1958, MPXV has caused sporadic human outbreaks in central and west Africa, with a mortality rate between 1% and 10%.1 Viral genomes from west Africa and the Congo Basin separate into two clades, the latter being more virulent.2 Recently, MPXV outbreaks have occurred in Sudan (2005), the Republic of the Congo and Democratic Republic of the Congo (2009), and the Central African Republic (2016).

中文翻译:


尼日利亚人猴痘病毒的基因组特征



猴痘病毒 (MPXV) 是一种大型双链 DNA 病毒,属于痘病毒科正痘病毒属。 MPXV 于 1958 年首次发现,在中非和西非引起了人类零星疫情,死亡率在 1% 至 10% 之间。 1来自西非和刚果盆地的病毒基因组分为两个分支,后者的毒性更强。 2最近,苏丹(2005 年)、刚果共和国和刚果民主共和国(2009 年)以及中非共和国(2016 年)爆发了 MPXV 疫情。
更新日期:2018-02-22
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