A ruthenium-catalyzed oxidative dearomatization of 2-alkyl- or 2-aryl-substituted indoles has been developed. When coupled with a cascade transformation, it provides a new system for the construction of indolin-3-ones bearing a C2-quaternary functionality. The reaction occurs readily with RuCl3·3H2O as a catalyst in acetonitrile. 2-(3-Indolyl)-substituted indolin-3-ones were obtained in medium to high yields. A mechanism for the reaction is also proposed.

中文翻译：

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钌催化吲哚的氧化脱芳构化用于构建 C2-Quaternary Indolin-3-one

已经开发了钌催化的 2-烷基-或 2-芳基-取代的吲哚的氧化脱芳构化。当与级联变换结合使用时，它为构建具有 C2-四元功能的 indolin-3-ones 提供了一个新系统。在乙腈中用 RuCl3·3H2O 作为催化剂很容易发生反应。2-(3-Indolyl)-取代的 indolin-3-ones 以中等至高产率获得。还提出了反应机理。