Young women with breast cancer have always caught the attention of both clinicians and researchers, despite this group being a rarity. Several factors distinguish the biology of both breast cancer in young patients and the patients themselves from that of tumours and patients who are diagnosed later in life. Additionally, the cancers might be associated with a previous pregnancy or have a pathogenesis that is based on a genetic predisposition; some data even imply that both cancers associated with a previous pregnancy and a genetic predisposition to cancer might be directly connected.

中文翻译：

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年轻女性中的乳腺癌：BRCA1或BRCA2突变重要吗？

乳腺癌的年轻女性一直吸引着临床医生和研究人员的注意，尽管这一群体非常罕见。有几个因素将年轻患者和患者本身的生物学与肿瘤和后来被诊断出的患者的生物学区别开来。此外，这些癌症可能与先前的怀孕有关，或者具有基于遗传易感性的发病机制。一些数据甚至暗示与先前怀孕相关的癌症和癌症的遗传易感性都可能直接相关。