Ferromagnetic particles (FMPs) have attracted a large amount of attention for tumor treatment in recent decades in the form of magnetic hyperthermia and thermoablation therapies. Previous research has commonly focused on the improvement of the specific loss power and the increase in the particle concentration to enhance the heating temperature during hyperthermia. Instead of magnetic hyperthermia with passive particles, here a feasible approach of using reconfigurable swarms of ferromagnetic colloidal particles is reported to realize enhanced local hyperthermia. The concentration of the particle swarm can be tuned up to 500% of the original particle concentration via reversible pattern transformation, i.e., shrinking and swelling. The FMP swarms with a controllable pattern size show their potential for directed energy delivery and offer a new strategy for realizing a highly localized heating effect using a low dose of the active FMPs.

中文翻译：

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铁磁胶体的可重构群以增强局部热疗

近几十年来，铁磁颗粒（FMP）以磁热疗和热消融疗法的形式引起了肿瘤治疗的广泛关注。先前的研究通常集中在提高比损耗功率和增加颗粒浓度以提高热疗期间的加热温度上。代替具有被动粒子的磁热疗，这里报道了一种使用可重构铁磁胶体粒子群的可行方法来实现增强的局部热疗。粒子群的浓度可以通过可逆的模式转换（即收缩和溶胀）调整到原始粒子浓度的500％。