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Blue‐Fluorescent Probes for Lipid Droplets Based on Dihydrochromeno‐Fused Pyrazolo‐ and Pyrrolopyridines
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2018-03-30 , DOI: 10.1002/ejoc.201701633
Martín Becerra-Ruiz 1 , Victor Vargas 1 , Patricio Jara 1 , Cristian Tirapegui 2, 3 , Carlos Carrasco 4 , Marco Nuñez 4 , Nicolás Lezana 1 , Antonio Galdámez 1 , Marcelo Vilches-Herrera 1
Affiliation  

Fluorescent probes allow the observation, detection, and distribution of living objects in the intracellular space. Because lipid storage is associated with the pathogenesis of highly prevalent metabolic diseases, the detection of lipid droplets, a type of subcellular organelle, is important. Herein, the synthesis of two series of blue‐fluorescent probes is reported.
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中文翻译:

蓝荧光探针用于基于二氢色胺基吡唑并吡咯并吡啶的脂质滴

荧光探针可以观察,检测和分布细胞内空间中的生物。由于脂质的储存与高度流行的代谢疾病的发病机理有关,因此,检测脂滴(一种亚细胞细胞器)非常重要。本文报道了两个系列的蓝色荧光探针的合成。
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更新日期:2018-03-30
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