In this article, the silk fibroin (SF)/graphene oxide (GO)-blended nanofibers with one bioinspired nanostructure are fabricated via electrospinning. The morphology, chemical structure, antibacterial activity, and biocompatibility of the blending nanofibers are investigated. The results indicate that GO plays an important role in preparing the distinctive bioinspired structure. The antibacterial activity and in vivo cell culture test demonstrate that blending of GO could improve the antibacterial activity and biocompatibility of SF nanofibers. The blended nanofibers developed in this study may have considerable potential for wound dressing applications.

中文翻译：

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改善氧化石墨烯修饰的生物启发静电纺丝素蛋白纳米纤维的抗菌活性和生物相容性。

在本文中，通过静电纺丝制备了一种具有生物启发性纳米结构的丝素蛋白（SF）/氧化石墨烯（GO）混合纳米纤维。研究了混合纳米纤维的形态，化学结构，抗菌活性和生物相容性。结果表明，GO在制备独特的生物启发结构中起着重要作用。抗菌活性和体内细胞培养试验表明，GO的掺混可以改善SF纳米纤维的抗菌活性和生物相容性。在这项研究中开发的混合纳米纤维在伤口敷料应用中可能具有相当大的潜力。