Diabetes: Towards a coxsackievirus B-based vaccine to combat T1DM

Diabetes: Towards a coxsackievirus B-based vaccine to combat T1DM, Published online: 12 January 2018; doi:10.1038/nrendo.2017.184

The role of group B coxsackieviruses (CVB) in the pathogenesis of type 1 diabetes mellitus (T1DM) remains controversial. A recent report by Stone et al. showed that a CVB1-based vaccine can protect against both CVB1 infection and CVB1-induced T1DM in mouse models. This tool could help to elucidate the relationship between CVB and T1DM.

中文翻译：

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糖尿病：针对基于柯萨奇病毒B的疫苗抗击T1DM

糖尿病：针对基于柯萨奇病毒B的疫苗抗击T1DM

糖尿病：针对基于柯萨奇B病毒的疫苗来对抗T1DM，在线发布：2018年1月12日; doi：10.1038 / nrendo.2017.184

B型柯萨奇病毒（CVB）在1型糖尿病（T1DM）发病机理中的作用仍存在争议。Stone等人的最新报告。结果表明，基于CVB1的疫苗可以在小鼠模型中预防CVB1感染和CVB1诱导的T1DM。该工具可以帮助阐明CVB和T1DM之间的关系。