The completely autotrophic nitrogen removal over nitrite (CANON) process is an important component of energy self-sufficient sewage treatment plants, and the use of aerobic granular sludge is a profitable choice for the CANON process. In this study, the performance and microbial characteristics of CANON granular sludge were investigated for treating synthetic and mainstream domestic sewage. The average nitrogen removal rate (NRR) was 3.22 kg N m⁻³ d⁻¹ during the high-rate operating period with high MLSS (4.09 g L⁻¹) and DO (∼1.0 mg L⁻¹) for treating synthetic sewage. When the influent was mainstream sewage, the average NRR was 1.11 kg N m⁻³ d⁻¹. The effluent nitrate concentration was very low, and nitrate build-up was not found. High-throughput pyrosequencing results indicated that, Nitrosomonas and Candidatus Brocadia were the dominant genus in ammonia oxidizing bacteria (AOB) and anaerobic AOB (AAOB), respectively. The proportions of AOB and AAOB decreased during mainstream sewage treatment, but the reactor maintained good performance. The results confirmed the feasibility of using CANON granular sludge for treating mainstream sewage.

完全自养的亚硝酸盐脱氮（CANON）工艺是能源自给自足的污水处理厂的重要组成部分，好氧颗粒污泥的使用是CANON工艺的有利选择。在这项研究中，研究了CANON颗粒污泥在处理合成和主流生活污水方面的性能和微生物特性。在高速率运行期间，平均ML去除率（NRR）为3.22 kg N m ^-3  d ^-1，其中MLSS（4.09 g L ^-1）和DO（〜1.0 mg L ^-1）高，用于处理合成污水。当进水为主流污水时，平均NRR为1.11 kg N m ^-3  d ^-1。出水硝酸盐浓度非常低，没有发现硝酸盐积聚。高通量焦磷酸测序结果表明，亚硝化单胞和暂定Brocadia均氨氧化细菌的优势属（AOB）和厌氧分别AOB（AAOB）。在主流污水处理过程中，AOB和AAOB的比例下降，但反应器保持了良好的性能。结果证实了使用CANON颗粒污泥处理主流污水的可行性。