Cover Picture: Intracellular Delivery of Native Proteins Facilitated by Cell-Penetrating Poly(disulfide)s (Angew. Chem. Int. Ed. 6/2018),Angewandte Chemie International Edition

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Cover Picture: Intracellular Delivery of Native Proteins Facilitated by Cell-Penetrating Poly(disulfide)s (Angew. Chem. Int. Ed. 6/2018)
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2018-01-11 , DOI: 10.1002/anie.201800062
Linghui Qian ₁ , Jiaqi Fu ₁ , Peiyan Yuan ₁ , Shubo Du ₁ , Wei Huang ₂ , Lin Li ₂ , Shao Q. Yao ₁

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Intracellular Transport A method for the delivery of native proteins into the cytosol of live mammalian cells with immediate bioavailability is described by L. Li, S. Q. Yao et al. in their Communication on page 1532. They report novel conjugation chemistries capable of covalent modification of native proteins with cell-penetrating poly(disulfide)s (CPDs). The picture shows a classical Chinese painting, with the boat representing CPDs providing the passengers (proteins) speedy travel to the intended destination (cell).

更新日期：2018-01-29

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