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Pitfalls of the healthy vaccinee effect
The Lancet ( IF 168.9 ) Pub Date : 2018-01-13 , DOI: 10.1016/s0140-6736(18)30017-5
Salaheddin M Mahmud , Christiaan H Righolt

We read with interest the Article by Helen Petousis-Harris and colleagues (Sept 30, 2017, p 1603),1 which showed that the vaccine against outer membrane vesicle meningococcal B was 31% effective in reducing gonorrhoea among attendees of 11 clinics in New Zealand for patients with sexually transmitted infections. We disagree, however, with the authors' claims that their “findings provide experimental evidence that these vaccines could offer moderate cross-protection against [gonorrhoea]”.

中文翻译:

健康的疫苗效果的陷阱

我们感兴趣地阅读了Helen Petousis-Harris及其同事的文章(2017年9月30日,第1603页),其中1显示在新西兰11家诊所的参与者中,针对外膜囊泡脑膜炎球菌B的疫苗在减少淋病方面有效率为31%适用于性传播感染的患者。但是,我们不同意作者的主张,即他们的“发现提供了实验证据,证明这些疫苗可以提供针对[性腺炎]的中等交叉保护作用”。
更新日期:2018-01-12
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