Thiophenols are a class of highly toxic environmental pollutant, hence it is very necessary to monitor thiophenols in environment and living cells with an efficient and reliable method. Herein, a novel fluorescent probe for thiophenols has been developed, which exhibited a colorimetric and fluorescence turn-on dual response towards thiophenols with good selectivity and fast response. The sensing mechanism for thiophenols was attributed to nucleophilic substitution reaction, which was confirmed by HPLC. The probe exhibited good recovery (from 90% to 107%) and low limit of detection for thiophenols (37 nM) in industrial wastewater. Moreover, the probe has been successfully employed to visualize thiophenol in living cells. Therefore, the fluorescent probe has good capability for monitoring thiophenols in environmental samples and biological systems.

硫酚是一类剧毒的环境污染物，因此非常有必要使用一种有效而可靠的方法来监测环境和活细胞中的硫酚。在本文中，已经开发了一种新型的硫酚荧光探针，该探针表现出对硫酚的比色和荧光开启双重响应，具有良好的选择性和快速响应性。苯酚的感测机理归因于亲核取代反应，这已通过HPLC证实。该探针具有良好的回收率（从90％到107％），并且对工业废水中的苯酚（37 nM）的检测限较低。此外，该探针已成功用于可视化活细胞中的苯酚。因此，该荧光探针具有良好的监测环境样品和生物系统中苯酚的能力。