Photoredox-mediated copper-catalyzed hydroxylation of (hetero)aryl halides (including chlorides, bromides, and iodides) with O₂ at room temperature has been developed. Preliminary mechanistic studies indicate no arylcopper intermediate and that aryl radicals are involved in this procedure. ¹⁸O-labeling experiments confirm the hydroxyl oxygen atom originated from molecular oxygen.

中文翻译：

---

（杂）芳基卤化物与分子氧的协同光催化铜羟基化反应

在室温下用O ₂光氧化还原介导的铜催化（杂）芳基卤化物（包括氯化物，溴化物和碘化物）的铜催化羟基化作用。初步的机理研究表明，没有芳基铜中间体，并且芳基自由基也参与了该程序。^18个O标记实验证实了羟基氧原子起源于分子氧。