An efficient palladium‐catalyzed direct oxidative esterification reaction of indoles with both aliphatic and aromatic carboxylic acids is reported. The use of Ag₂CO₃ is crucial to this transformation, as it functions as both a base and an oxidant for the regeneration of the palladium(II) catalyst. This methodology represents a novel prospect for C(sp²)−H acyloxylation and will promote interest in direct C(sp²)−H esterification.

中文翻译：

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钯催化的C3位吲哚的直接氧化酯化反应：C（sp2）-H酰氧基化的新前景

据报道，吲哚与脂肪族和芳香族羧酸均能有效地进行钯催化的直接氧化酯化反应。Ag ₂ CO ₃的使用对于这种转化至关重要，因为它既可以作为碱，也可以作为氧化剂用于钯（II）催化剂的再生。这种方法学代表了C（sp ²）-H酰氧基化的新前景，并将促进人们对直接C（sp ²）-H酯化的兴趣。