In this study, a novel resonance light scattering (RLS) sensor was synthesized using polyacrylonitrile nanofibers decorated with magnetic carbon dots ([email protected]) nanocomposite and applied for famotidine (FMD) determination. The [email protected] nanocomposite was synthesized by combining electrospinning and a simple one-step hydrothermal method. Different methods were applied in order to characterize the [email protected] nanocomposite such as: scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD). Light scattering properties of the synthesized nanocomposite in the presence or absence of FMD have been selected as the detection signal considering the fact that FMD addition increases the RLS intensities of the system. Thus, the prepared nanocomposite was employed as a RLS sensor to detect FMD. A linear response was observed under the optimal conditions in range of 0.15–50.0 μmol L⁻¹ with detection limit of 0.04 μmol L⁻¹. The [email protected] nanocomposite was effectively capable in determining FMD in real samples and the results were close to those results obtained by reversed-phase HPLC method (RP-HPLC).

在这项研究中，使用装饰有磁性碳点（[电子邮件保护]）纳米复合材料的聚丙烯腈纳米纤维合成了新型共振光散射（RLS）传感器，并将其用于法莫替丁（FMD）的测定。[电子邮件保护]纳米复合材料是通过电纺丝和简单的一步水热法相结合而合成的。为了表征[受电子邮件保护的]纳米复合材料，采用了不同的方法，例如：扫描电子显微镜（SEM），傅立叶变换红外光谱（FT-IR），透射电子显微镜（TEM），X射线光电子光谱（XPS）和X射线衍射（XRD）。考虑到添加FMD会增加系统的RLS强度这一事实，已选择存在或不存在FMD的合成纳米复合材料的光散射特性作为检测信号。因此，将制备的纳米复合材料用作RLS传感器来检测FMD。在最佳条件下，在0.15-50.0μmolL范围内观察到线性响应^-1的检测极限为0.04μmolL ^-1。[电子邮件保护的]纳米复合材料能够有效地测定实际样品中的口蹄疫，其结果与通过反相HPLC方法（RP-HPLC）获得的结果相近。