当前位置:
X-MOL 学术
›
Tetrahedron Lett.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Transition-metal-free synthesis of aromatic amines via the reaction of benzynes with isocyanates
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-01-09 , DOI: 10.1016/j.tetlet.2018.01.022 Jeong Hoon Seo , Haye Min Ko
中文翻译:
通过苯炔与异氰酸酯的反应无过渡金属合成芳族胺
更新日期:2018-01-09
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-01-09 , DOI: 10.1016/j.tetlet.2018.01.022 Jeong Hoon Seo , Haye Min Ko
An unexpected reaction between benzynes and isocyanates to generate aromatic amines has been developed under transition-metal-free conditions. The in situ prepared anions formed through cleavage of the NC bond in isocyanates, reacted with aryne precursors to afford various aniline derivatives in moderate to excellent yield and tolerated various substituents on the o-silyl aryl triflate and the isocyanate.
中文翻译:
通过苯炔与异氰酸酯的反应无过渡金属合成芳族胺
在不含过渡金属的条件下,苯并炔与异氰酸酯发生意外反应生成芳族胺。在原位制备过N开裂而形成的阴离子C键中的异氰酸酯,具有芳炔前体在中等至良好的产率反应,得到各种苯胺衍生物和耐受上各种取代基ø -甲硅烷基三氟甲磺酸的芳基和异氰酸酯。