A novel alternative bioconversion and chemical transformation method for valorisation of food and beverage (F&B) waste to hydroxymethylfurfural (HMF) is reported. Solid-to-liquid ratio of 70% was applied to hydrolyse F&B waste by glucoamylase and sucrase to yield a hydrolysate consisted of glucose and fructose. After impurity removal using chromatography columns, the purified hydrolysate was processed by glucose isomerase to produce syrup with a fructose-to-glucose ratio of 1:1. After removal of the residual impurities using ion exchange columns, Simulated Moving Bed system was applied to separate sugars in fructose-glucose syrup. The resultant high-fructose syrup contained 89.0 g/L fructose, which was demonstrated as an ideal feedstock for the synthesis of HMF. By employing a commercial solid acid catalyst (Amberlyst 36), 71 mol% HMF with a high selectivity of 77 mol% was generated from this high-fructose syrup under mild microwave heating at 140 °C within 40 min. The increase in catalyst loading accelerated both HMF formation and HMF-consuming side reactions, underscoring the trade-off between the conversion rate and product selectivity. The solid catalyst can be recovered and successfully reused for four runs with the HMF yield at 70 mol%. An overall conversion yield of 30 g HMF/kg F&B waste was achieved. This work emphasises a novel integration of chemical and biological technologies for selective production of HMF from mixed F&B waste.

报道了一种新颖的替代性生物转化和化学转化方法，用于将食品和饮料（F＆B）废物估价为羟甲基糠醛（HMF）。固液比为70％，可通过葡糖淀粉酶和蔗糖酶水解食品和饮料废物，以产生由葡萄糖和果糖组成的水解产物。在使用色谱柱去除杂质后，纯化的水解产物通过葡萄糖异构酶进行处理，以产生果糖与葡萄糖的比例为1：1的糖浆。使用离子交换柱去除残留杂质后，将模拟移动床系统应用于分离果糖-葡萄糖浆中的糖。所得的高果糖糖浆包含89.0 g / L的果糖，这被证明是合成HMF的理想原料。通过使用市售的固体酸催化剂（Amberlyst 36），该高果糖糖浆在温和的微波加热下于140°C在40分钟内产生了71 mol％的HMF，具有77 mol％的高选择性。催化剂载量的增加加速了HMF的形成和消耗HMF的副反应，强调了转化率和产物选择性之间的权衡。可以回收固体催化剂并成功地将其再使用四次，HMF收率为70摩尔％。总转化率达到30 g HMF / kg餐饮废弃物。这项工作着重于化学和生物技术的新颖结合，以便从混合的食品和饮料废物中选择性生产HMF。催化剂载量的增加加速了HMF的形成和消耗HMF的副反应，强调了转化率和产物选择性之间的权衡。可以回收固体催化剂并成功地将其再使用四次，HMF收率为70摩尔％。总转化产量为30 g HMF / kg餐饮废物。这项工作着重于化学和生物技术的新颖结合，以便从混合的食品和饮料废物中选择性生产HMF。催化剂载量的增加加速了HMF的形成和消耗HMF的副反应，强调了转化率和产物选择性之间的权衡。可以回收固体催化剂并成功地将其再使用四次，HMF收率为70摩尔％。总转化产量为30 g HMF / kg餐饮废物。这项工作着重于化学和生物技术的新颖结合，以便从混合的食品和饮料废物中选择性生产HMF。