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The Enduring Legacy of 250 Years of Pharmacology in Edinburgh
Annual Review of Pharmacology and Toxicology ( IF 12.5 ) Pub Date : 2018-01-08 00:00:00 , DOI: 10.1146/annurev-pharmtox-010617-052901
John S. Kelly 1 , Angus V.P. Mackay 2
Affiliation  

In 1768, 250 years ago, the University of Edinburgh appointed Francis Home to the first chair of materia medica, the accumulated knowledge of materials used in healing. Francis Home and his colleagues were determined to improve the quality of medical training in Edinburgh by introducing a final examination and compiling a catalog of medicines validated by the Royal College of Physicians of Edinburgh. The catalog, known as the Edinburgh Pharmacopoeia, was a great success, partly due to the orderly nature of its contents, its routine editing to eliminate worthless entries, and the introduction of new treatments whose preparation was precisely documented. In a relatively short time, the worth of the Edinburgh Pharmacopoeia was recognized throughout Europe, America, and the British Empire. Today, the British and European Pharmacopoeias are catalogs of publicly available, legally enforceable standards for active pharmaceutical ingredients and finished dosage forms of pharmaceutical products and medical devices. Home and the many luminaries who succeeded him would surely take pleasure and pride in the fact that the mantra of today's medicines regulators worldwide is little different from that of these early visionaries: “To take better advantage of the best possible science in the service of the public health and our health-care systems” (1, p. 492).

中文翻译:


爱丁堡药理学250年的悠久传统

250年前的1768年,爱丁堡大学任命弗朗西斯·霍姆(Francis Home)担任本草学的第一任主席,这是治疗所用材料的累积知识。弗朗西斯·霍姆(Francis Home)和他的同事们决心通过引入期末考试并编制一份由爱丁堡皇家内科医师学院确认的药物目录,来提高爱丁堡医学培训的质量。该目录被称为“爱丁堡药典”,取得了巨大成功,部分原因是目录内容的井井有条,定期进行编辑以消除无用的条目,并引入了精确记录了其制备方法的新疗法。在相对较短的时间内,爱丁堡药典的价值在整个欧洲,美洲和大英帝国得到认可。今天,《英国药典》和《欧洲药典》是活性药物成分以及药物产品和医疗设备的最终剂型的可公开获得的,法律上可执行的标准目录。霍姆和接任他的许多名人肯定会感到高兴和自豪,因为当今世界范围内的药品监管机构的口头禅与这些早期有远见的人没有什么不同:“为了更好地利用最佳科学,公共卫生和我们的卫生保健系统”(第1页,第492页)。

更新日期:2018-01-08
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