Metal‐Free Azidoarylation of Vinylcyclopropanes for the Synthesis of N3‐Containing Dihydronaphthalenes,Asian Journal of Organic Chemistry

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Metal‐Free Azidoarylation of Vinylcyclopropanes for the Synthesis of N3‐Containing Dihydronaphthalenes
Asian Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2018-01-08 , DOI: 10.1002/ajoc.201700683
Zong-Rui Li ₁ , Dun-Qi Wu ₁ , Jian Sun ₁ , Jing Shen ₁ , Qing-Hai Deng ₁

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An efficient methodology for the direct metal‐free azidoarylation of vinylcyclopropanes using trimethylsilyl azide as the N₃‐transfer reagent is described. The reaction can be performed on a gram scale and a series of N₃‐containing dihydronaphthalene derivatives (20 examples) were prepared in good to high yields under mild reaction conditions. Furthermore, three of these organic azides were selected for facile conversion into the corresponding 1,2,3‐triazoles or amino derivatives.

中文翻译：

乙烯基环丙烷的无金属叠氮芳基化反应用于合成含N3的二氢萘

描述了一种使用三甲基叠氮化硅作为N ₃转移试剂进行乙烯基环丙烷直接无金属叠氮芳基化的有效方法。该反应可以以克为单位进行，并且在温和的反应条件下以高到高收率制备了一系列含N ₃的二氢萘衍生物（20个实例）。此外，选择了其中的三种有机叠氮化物以轻松转化为相应的1,2,3-三唑或氨基衍生物。

更新日期：2018-01-08

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