The Ir-catalyzed asymmetric hydrogenation of simple aromatic ketones with chiral ferrocenyl P,N,N-ligands has been developed. Under the optimized conditions, a wide range of ketones were hydrogenated to afford the corresponding chiral alcohols in good to excellent enantioselectivities (up to 98% ee).

中文翻译：

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Ir手性二茂铁二茂铁P，N，N配体对酮的不对称催化加氢

已开发了具有手性二茂铁基P，N，N-配体的简单芳族酮的Ir催化不对称加氢反应。在优化的条件下，将广泛的酮氢化，得到相应的手性醇，对映体的对映选择性好至极佳（ee高达98％）。