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Adipose tissue: The dysfunctional adipocyte — a cancer cell's best friend
Nature Reviews Endocrinology ( IF 31.0 ) Pub Date : 2018-01-05 , DOI: 10.1038/nrendo.2017.174
Zhuzhen Zhang , Philipp E. Scherer

Adipose tissue: The dysfunctional adipocyte — a cancer cell's best friend

Adipose tissue: The dysfunctional adipocyte — a cancer cell's best friend, Published online: 05 January 2018; doi:10.1038/nrendo.2017.174

The interactions of adipocytes with tumour cells have been extensively scrutinized. The adipocyte's mitogenic influence on tumour cells is attributed to several hormonal, growth factor and adipokine effects. A recent study has expanded our understanding of how adipocytes promote tumour progression by demonstrating that adipocytes actively catabolize the chemotherapeutic agent daunorubicin.


中文翻译:

脂肪组织:功能异常的脂肪细胞-癌细胞的最好朋友

脂肪组织:功能异常的脂肪细胞-癌细胞的最好朋友

脂肪组织:功能失调的脂肪细胞-癌细胞最好的朋友,在线发布:2018年1月5日;doi:10.1038 / nrendo.2017.174

脂肪细胞与肿瘤细胞的相互作用已被广泛研究。脂肪细胞对肿瘤细胞的促有丝分裂作用归因于几种激素,生长因子和脂肪因子的作用。最近的研究通过证明脂肪细胞积极地分解代谢化疗药物柔红霉素,扩展了我们对脂肪细胞如何促进肿瘤进展的理解。
更新日期:2018-01-05
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