Abstract The present study has been focused on a facile strategy to fabricate an electrochemical sensor based on nickel oxide decorated Fe3O4 nanoparticles/poly(p-aminohippuric acid)-sodium dodecyl sulfate nanocomposite immobilized on the modified glassy carbon electrode (NiO@ Fe3O4-SH/PPAH-SDS/GCE). PPAH-SDS film was prepared by electropolymerization and nickel oxide nanostructures were deposited on the Fe3O4-SH/PPAH-SDS by electrochemical method. The as-synthesized nanocomposite was characterized by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) for morphological and elemental analysis, respectively and the electrochemical characteristics were studied by the cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) methods. The differential pulse voltammetry (DPV) was used for the sensitive determination of glucose in alkaline solution in two linear concentration ranges, 0.1–10.0 μM and 10.0–300.0 μM, with a detection limit of 0.13 μM (S/N = 3) based on the first linear range. Meanwhile, the presented sensor showed a promising performance for the quantification of glucose in human serum as a real sample reflecting the practicability of fabricated glucose sensor.

中文翻译：

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NiO/Fe 3 O 4 -SH/对氨基马尿酸纳米复合材料制成的非酶伏安葡萄糖传感器

摘要 本研究的重点是一种基于氧化镍修饰的 Fe3O4 纳米颗粒/聚（对氨基马尿酸）-十二烷基硫酸钠纳米复合材料固定在改性玻璃碳电极（NiO@Fe3O4-SH/ PPAH-SDS/GCE）。通过电聚合制备PPAH-SDS薄膜，并通过电化学方法将氧化镍纳米结构沉积在Fe3O4-SH/PPAH-SDS上。通过扫描电子显微镜 (SEM) 和能量色散谱 (EDS) 分别对合成的纳米复合材料进行形态和元素分析，并通过循环伏安法 (CV) 和电化学阻抗谱 (EIS) 方法研究其电化学特性。差分脉冲伏安法 (DPV) 用于灵敏测定碱性溶液中葡萄糖在两个线性浓度范围，0.1-10.0 μM 和 10.0-300.0 μM，检测限为 0.13 μM (S/N = 3)，基于第一个线性范围。同时，所提出的传感器在定量人血清中的葡萄糖方面表现出良好的性能，作为真实样品，反映了制造的葡萄糖传感器的实用性。