Directed Decarbonylation of Unstrained Aryl Ketones via Nickel-Catalyzed C−C Bond Cleavage,Journal of the American Chemical Society

当前位置： X-MOL 学术 › J. Am. Chem. Soc. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Directed Decarbonylation of Unstrained Aryl Ketones via Nickel-Catalyzed C−C Bond Cleavage
Journal of the American Chemical Society ( IF 14.4 ) Pub Date : 2018-01-08 , DOI: 10.1021/jacs.7b11591
Tian-Tian Zhao ₁ , Wen-Hua Xu ₁ , Zhao-Jing Zheng ₂ , Peng-Fei Xu ₂ , Hao Wei ₁

Affiliation

The nickel-catalyzed decarbonylation of unstrained diaryl ketones has been developed. The reaction is catalyzed by a combination of Ni(cod)2 and an electron-rich N-heterocyclic carbene ligand. High functional group tolerance and excellent yields (up to 98%) are observed. This strategy provides an alternative and versatile approach to construct biaryls using an inexpensive nickel catalyst.

中文翻译：

通过镍催化的 C-C 键裂解对未受约束的芳基酮进行定向脱羰

镍催化的无应变二芳基酮的脱羰已经被开发出来。该反应由 Ni(cod)2 和富含电子的 N-杂环卡宾配体的组合催化。观察到高官能团耐受性和优异的产率（高达 98%）。该策略提供了一种使用廉价镍催化剂构建联芳基化合物的替代和通用方法。

更新日期：2018-01-08

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11