Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties†,Journal of Materials Chemistry B

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Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties†
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2018-01-05 00:00:00 , DOI: 10.1039/c7tb02864d
Yu Zhang _{1,

2,

3,

4,

5} , Cui Huang _{5,

6,

7,

8,

9} , Jiang Chang _{1,

2,

3,

4,

5}

Affiliation

Ca-Doped mesoporous SiO₂ (MCS) nanoparticles with diameter of 230 nm were synthesized by a sol–gel method with some modification. As inorganic fillers, they improved the mechanical properties of the resin composites with 5%, 10%, 20% addition (5RC, 10RC, 20RC). After soaking in the simulated oral fluid (SOF), the resin composites showed excellent activity in inducing apatite-mineralization. As mesoporous nanoparticles, they can be used as carriers for loading the antibacterial drug Ciprofloxacin hydrochloride (CiH). The antibacterial testing of the resin composites with MCS-CiH (5RC-CiH, 10RC-CiH, 20RC-CiH) demonstrated excellent antibacterial effects. The incorporation of Ca-doped mesoporous SiO₂ into dental resin is a suitable approach for improving the properties of the dental resin, and the MCS/resin composites have the potential for application in preventing secondary-caries.

中文翻译：

钙掺杂的介孔SiO ₂ /牙科树脂复合材料，具有增强的机械性能，生物活性和抗菌性能†

通过溶胶-凝胶法并作了一些修改，合成了直径230 nm的Ca掺杂介孔SiO ₂（MCS）纳米颗粒。作为无机填料，它们通过添加5％，10％，20％（5RC，10RC，20RC）改善了树脂复合材料的机械性能。浸泡在模拟口腔液（SOF）中后，树脂复合材料在诱导磷灰石矿化方面表现出出色的活性。作为介孔纳米颗粒，它们可用作载有抗菌药物盐酸环丙沙星（CiH）的载体。MCS-CiH（5RC-CiH，10RC-CiH，20RC-CiH）对树脂复合材料的抗菌测试显示出优异的抗菌效果。掺钙的介孔SiO ₂的掺入将其加入牙科树脂中是改善牙科树脂性能的合适方法，MCS /树脂复合材料具有预防二次龋齿的潜力。

更新日期：2018-01-05

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