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Ca-Doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties†
Journal of Materials Chemistry B ( IF 6.1 ) Pub Date : 2018-01-05 00:00:00 , DOI: 10.1039/c7tb02864d
Yu Zhang 1, 2, 3, 4, 5 , Cui Huang 5, 6, 7, 8, 9 , Jiang Chang 1, 2, 3, 4, 5
Affiliation  

Ca-Doped mesoporous SiO2 (MCS) nanoparticles with diameter of 230 nm were synthesized by a sol–gel method with some modification. As inorganic fillers, they improved the mechanical properties of the resin composites with 5%, 10%, 20% addition (5RC, 10RC, 20RC). After soaking in the simulated oral fluid (SOF), the resin composites showed excellent activity in inducing apatite-mineralization. As mesoporous nanoparticles, they can be used as carriers for loading the antibacterial drug Ciprofloxacin hydrochloride (CiH). The antibacterial testing of the resin composites with MCS-CiH (5RC-CiH, 10RC-CiH, 20RC-CiH) demonstrated excellent antibacterial effects. The incorporation of Ca-doped mesoporous SiO2 into dental resin is a suitable approach for improving the properties of the dental resin, and the MCS/resin composites have the potential for application in preventing secondary-caries.

中文翻译:

钙掺杂的介孔SiO 2 /牙科树脂复合材料,具有增强的机械性能,生物活性和抗菌性能

通过溶胶-凝胶法并作了一些修改,合成了直径230 nm的Ca掺杂介孔SiO 2(MCS)纳米颗粒。作为无机填料,它们通过添加5%,10%,20%(5RC,10RC,20RC)改善了树脂复合材料的机械性能。浸泡在模拟口腔液(SOF)中后,树脂复合材料在诱导磷灰石矿化方面表现出出色的活性。作为介孔纳米颗粒,它们可用作载有抗菌药物盐酸环丙沙​​星(CiH)的载体。MCS-CiH(5RC-CiH,10RC-CiH,20RC-CiH)对树脂复合材料的抗菌测试显示出优异的抗菌效果。掺钙的介孔SiO 2的掺入 将其加入牙科树脂中是改善牙科树脂性能的合适方法,MCS /树脂复合材料具有预防二次龋齿的潜力。
更新日期:2018-01-05
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