We describe the details of the first total synthesis of alangiumkaloids A (1) and B (2) through construction of an isoquinolinone framework formed by thermal cyclization of 2‐alkynylbenzaldehyde oxime to produce isoquinoline N‐oxide, followed by a Reissert–Henze‐type reaction.

中文翻译：

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两种8-氧代小ber碱生物碱的总合成：lang兰碱A和B

我们通过构造异喹啉酮骨架（由2-炔基苯甲醛肟热环化生成异喹啉N-氧化物，然后再形成Reissert-Henze型）形成异喹啉酮骨架，描述了首个总合成Alangiumkaloids A（1）和B（2）的细节。反应。