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Commentary: Unusual pancreatic cancer incidence and mortality patterns
International Journal of Epidemiology ( IF 6.4 ) Pub Date : 2017-08-14 , DOI: 10.1093/ije/dyx142
Claire M Vajdic , Maarit A Laaksonen

Pancreatic cancer, a high-burden cancer, is the 12th most common cancer and the seventh most common cause of cancer death globally.1 The accurate diagnosis of this internal malignancy is challenging in settings without access to medical imaging technology. Around 20–50% of cases are diagnosed only clinically, without microscopic assessment of a tissue sample. In 2012, the average age-standardized incidence and mortality rates in developed countries were 8.6 and 8.3 per 100‐000, respectively, in men and 5.9 and 5.5 per 100‐000, respectively, in women.1 As these rates suggest, relative survival is very poor, around 5–10% at 5 years.2,3 With an aggressive natural history, indistinct symptoms and no effective screening test or therapy, primary prevention is currently the best available strategy to reduce the burden of this malignancy....

中文翻译:

评论:异常胰腺癌的发病率和死亡率模式

胰腺癌是高负担的癌症,是全球第12大最常见的癌症和第七大最常见的癌症死亡原因。1在无法获得医学影像技术的情况下,对这种内部恶性肿瘤的准确诊断非常困难。大约20–50%的病例仅在临床上得到诊断,而没有对组织样本进行显微镜评估。2012年,发达国家的平均年龄标准化发病率和死亡率分别为男性每十万分之8.6和8.3,男性和女性每十万分之5.9和5.5。1正如这些比率所表明的,相对存活率非常低,在5年时约为5-10%。2 3 具有侵略性的自然病史,症状不明显且没有有效的筛查测试或疗法,一级预防目前是减轻这种恶性肿瘤负担的最佳可行策略。
更新日期:2018-01-05
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