Iron-Catalyzed Aerobic Oxidation and Annulation Reaction of Pyridine and α-Substituted Allenoate toward Functionalized Indolizine,Organic Letters

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Iron-Catalyzed Aerobic Oxidation and Annulation Reaction of Pyridine and α-Substituted Allenoate toward Functionalized Indolizine
Organic Letters ( IF 4.9 ) Pub Date : 2018-01-04 00:00:00 , DOI: 10.1021/acs.orglett.7b03696
Tao Jin ₁ , Zhongzhong Tang ₁ , Jie Hu ₁ , Hongdong Yuan ₁ , Yaoyao Chen ₁ , Chunju Li ₁ , Xueshun Jia _{1,

2} , Jian Li ₁

Affiliation

An iron-catalyzed reaction of pyridine and α-substituted allenoate has been disclosed. The present strategy incorporates the aerobic oxidation into annulation involving substituted allenoate, thus providing a new access to functionalized indolizine.

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