当前位置:
X-MOL 学术
›
Organometallics
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
An Improved Synthesis of Me4PCP and DMPE
Organometallics ( IF 2.5 ) Pub Date : 2018-01-04 00:00:00 , DOI: 10.1021/acs.organomet.7b00780 Travis T. Lekich 1 , Phoebe G. Askelson 1 , Ryan K. Burdick 1 , D. Michael Heinekey 1
Organometallics ( IF 2.5 ) Pub Date : 2018-01-04 00:00:00 , DOI: 10.1021/acs.organomet.7b00780 Travis T. Lekich 1 , Phoebe G. Askelson 1 , Ryan K. Burdick 1 , D. Michael Heinekey 1
Affiliation
We present a new synthetic method for the bis(dimethyl)phosphines Me4PCP (C6H4-2,6-(CH2P(CH3)2)2) and DMPE ((CH3)2PCH2CH2P(CH3)2) that starts from an aminophosphine, Et2NPMe2. Two equivalents of Et2NPMe2 react with the corresponding bis(alkyl bromide) to afford an oxygen- and moisture-stable aminophosphonium salt. NaAlH4 selectively reduces the aminophosphonium salt to the desired phosphine. Each step is high yielding and requires minimal purification.
中文翻译:
Me4 PCP和DMPE的改进合成
我们提出了一种新的合成方法,用于双(二甲基)膦Me4 PCP(C 6 H 4 -2,6-(CH 2 P(CH 3)2)2)和DMPE((CH 3)2 PCH 2 CH 2 P (CH 3)2)从氨基膦Et 2 NPMe 2开始。两当量的Et 2 NPMe 2与相应的双(烷基溴)反应,制得氧和湿气稳定的氨基phosph盐。NaAlH 4选择性地将氨基phosph盐还原为所需的膦。每个步骤产量高,需要最少的纯化。
更新日期:2018-01-05
中文翻译:
Me4 PCP和DMPE的改进合成
我们提出了一种新的合成方法,用于双(二甲基)膦Me4 PCP(C 6 H 4 -2,6-(CH 2 P(CH 3)2)2)和DMPE((CH 3)2 PCH 2 CH 2 P (CH 3)2)从氨基膦Et 2 NPMe 2开始。两当量的Et 2 NPMe 2与相应的双(烷基溴)反应,制得氧和湿气稳定的氨基phosph盐。NaAlH 4选择性地将氨基phosph盐还原为所需的膦。每个步骤产量高,需要最少的纯化。