Oxidative stress has been suggested to play a central role in the pathogenesis of diabetes, as well as other metabolic disorders. Naringin, a major flavanone glycoside in citrus species, has been shown to display strong antioxidant potential in in vitro and in vivo models of oxidative stress; however, the underlying protective mechanisms in diabetes are unclear.

中文翻译：

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柚皮苷通过抑制胰岛素缺乏型糖尿病小鼠的内源性途径和外源性途径，保护胰腺β细胞免受氧化应激诱导的细胞凋亡。

已经表明氧化应激在糖尿病以及其他代谢性疾病的发病机理中起着核心作用。柚皮素是柑橘类中的一种主要黄烷酮糖苷，已显示出在体外和体内氧化应激模型中显示出强大的抗氧化潜能。但是，尚不清楚糖尿病的潜在保护机制。