o-Chlorophenol (OCP) is a priority pollutant that poses serious health threats to the public. The following study designs a simple electrochemical system to monitor the concentration and toxicity of OCP. This system was primarily characterized by the integration of both physicochemical and biological monitoring procedures that had a synergistic effect between the functionalized carbon nanotubes and rhodamine B. This resulted in excellent electrocatalytic activities toward OCP and cellular purine bases. The peak current of OCP was linear with concentrations ranging from 0.05–125.0 μM and the detection limit was 0.028 μM under optimal testing conditions. There was an enhanced voltammetric signal detected that was caused by the guanine/xanthine of human hepatoma (HepG2) cells. The cytotoxicity of OCP to HepG2 cells was assessed using the proposed system. The obtained IC₅₀ value was 512.86 μM. This study provided a fast, label-free, and low-cost platform for the comprehensive assessment of OCP. This is highly beneficial for simplifying the environmental monitoring process.

Ø-氯酚（OCP）是一种优先污染物，会对公众构成严重的健康威胁。以下研究设计了一个简单的电化学系统来监控OCP的浓度和毒性。该系统的主要特点是整合了物理化学和生物学监测程序，在功能化碳纳米管和若丹明B之间产生了协同效应。这导致了对OCP和细胞嘌呤碱的出色电催化活性。在最佳测试条件下，OCP的峰值电流与浓度范围为0.05–125.0μM呈线性关系，检出限为0.028μM。检测到增强的伏安信号，该伏安信号是由人肝癌（HepG2）细胞的鸟嘌呤/黄嘌呤引起的。使用提出的系统评估了OCP对HepG2细胞的细胞毒性。获得的IC_50的值为512.86μM。该研究为OCP的综合评估提供了一个快速，无标签且低成本的平台。这对于简化环境监控过程非常有帮助。