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Synthesis of 2-Iodoazulenes by the Iododeboronation of Azulen-2-ylboronic Acid Pinacol Esters with Copper(I) Iodide
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2018-01-19 00:00:00 , DOI: 10.1021/acs.joc.7b02820
Masahiro Narita 1 , Toshihiro Murafuji 1, 2, 3 , Saki Yamashita 2 , Masayuki Fujinaga 3 , Kumiko Hiyama 3 , Yurie Oka 3 , Fumito Tani 4 , Shin Kamijo 1, 2 , Katsuya Ishiguro 1, 2
Affiliation  

Azulen-2-ylboronic acid pinacol ester, prepared by iridium-catalyzed C–H borylation of azulene, efficiently underwent iododeboronation with a stoichiometric amount of copper(I) iodide. This reaction allowed the synthesis of 2-iodoazulene in only two steps starting from azulene. This methodology was successfully applied to analogous azulenes.

中文翻译:

Azulen-2-基硼酸频哪醇酯与碘化铜(I)的碘脱硼合成2-碘唑啉

通过铱催化的z唑的CH硼氢化,制备的Azulen-2-基硼酸频哪醇酯与化学计量的碘化铜(I)有效地进行了碘脱硼作用。该反应允许从a烯开始仅两步合成2-碘io烯。该方法已成功地应用于类似的天青石。
更新日期:2018-01-19
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