A patient with refractory thrombotic thrombocytopenic purpura had anaphylaxis associated with rituximab that was mediated by human antichimeric antibodies. The patient was successfully treated with ofatumumab, with restoration of ADAMTS13 levels.

中文翻译：

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奥法木单抗用于利妥昔单抗相关过敏反应患者的TTP

难治性血栓性血小板减少性紫癜患者的过敏反应与利妥昔单抗有关，后者是由人抗嵌合抗体介导的。该患者已成功用ofatumumab治疗，并恢复了ADAMTS13水平。