As a metal-free reagent, tert-butylnitrite (TBN) initiated aerobic sp³ C–H bond oxidation of glycine esters was achieved, providing a series of quinoline-2-carboxylates in good yields. The mechanistic investigation revealed that in the presence of molecular oxygen, TBN derived radicals were involved in the C–H bond oxidation and the terminal aromatization.

中文翻译：

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TBN作为一种无金属试剂，可引发甘氨酸酯的sp ³ C–H官能化：喹啉-2-羧酸酯的合成

作为一种不含金属的试剂，可实现叔丁基亚硝酸盐（TBN）引发的甘氨酸酯的好氧sp ³ C–H键氧化，从而以良好的收率提供了一系列的喹啉-2-羧酸酯。机理研究表明，在存在分子氧的情况下，TBN衍生的自由基参与了C–H键的氧化和末端芳构化。