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Protocol for the Incorporation of γ-Amino Acids into Peptides: Application to (−)-Shikimic Acid Based 2-Amino-Methylcyclohexanecarboxylic Acids
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2018-01-17 00:00:00 , DOI: 10.1021/acs.joc.7b02671 Marcos A. González 1 , Amalia M. Estévez 1 , María Campos 1 , Juan C. Estévez 1 , Ramón J. Estévez 1
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2018-01-17 00:00:00 , DOI: 10.1021/acs.joc.7b02671 Marcos A. González 1 , Amalia M. Estévez 1 , María Campos 1 , Juan C. Estévez 1 , Ramón J. Estévez 1
Affiliation
The first example of a new protocol for the incorporation of γ-amino acids into peptides is reported. It involved a shikimic acid based stereoselective synthesis polyhydroxylated-2-nitromethylcyclohexanecarboxylic acids, which were directly incorporated into peptides.
中文翻译:
将γ-氨基酸掺入肽中的协议:基于(-)-草酸的2-氨基-甲基环己烷甲酸的应用
报道了将γ-氨基酸掺入肽的新方案的第一个例子。它涉及基于sh草酸的立体选择性合成多羟基化的2-硝基甲基环己烷羧酸,将其直接掺入肽中。
更新日期:2018-01-17
中文翻译:
将γ-氨基酸掺入肽中的协议:基于(-)-草酸的2-氨基-甲基环己烷甲酸的应用
报道了将γ-氨基酸掺入肽的新方案的第一个例子。它涉及基于sh草酸的立体选择性合成多羟基化的2-硝基甲基环己烷羧酸,将其直接掺入肽中。