Cancer is a real menace to all societies globally since it is the leading cause of premature mortality in men and women. The incidence of malignancies is enhancing as a result of plenty factors. Physically and economically concerns that occur in cancers patients cannot be neglected. However, current diagnostic methods and cure duration do not fulfill patients requirements. Therefore, it is essential to detect and diagnose cancer biomarkers as soon as possible and overcome the current burdens. Novel aptasensors is emerging as one of the most promising strategies for early recognition of cancer. Aptamers an artificial DNA or RNA sequences, possess plenty of merits such as easy production, modification of their structure, lower immunogenicity, and high affinity to target that pave the way for early detection of cancer biomarkers. This review attempts to list novel and advanced investigation progress of aptamers in biosensor platforms for diagnosing of malignancies.

癌症是全球所有社会的真正威胁，因为它是男女过早死亡的主要原因。由于多种因素，恶性肿瘤的发生率正在增加。在癌症患者中发生的生理上和经济上的顾虑不能忽略。但是，当前的诊断方法和治愈时间不能满足患者的要求。因此，必须尽快检测和诊断癌症生物标志物并克服当前的负担。新型适体传感器正在成为癌症早期识别的最有希望的策略之一。适配人工DNA或RNA序列，具有许多优点，例如易于生产，结构修饰，较低的免疫原性和对靶标的高亲和力，为癌症生物标志物的早期检测铺平了道路。