Biocompatibility of cinnamoyl-modified carbohydrate materials is not well-known, while they are attracting attention as a photoreactive material. In order to investigate biocompatible properties of cinnamoyl-modified carbohydrate, hydroxypropyl cellulose (HPC) was reacted with cinnamoyl chloride to yield cinnamoyl-modified HPC (HPC-C) for a cell proliferation test. HPC-Cs with three different degrees of substitution (DS) were prepared by changing a feed ratio of cinnamoyl chloride to HPC. The DS of the products ranged from 1.3 to 3.0 per one hydroxylpropyl anhydroglucose unit. Thermal analysis using DSC and TGA showed that the HPC-C with higher DS has a glass transition temperature and higher thermal stability. Ultraviolet (UV) light was irradiated on the HPC-C thin films, and changes in the UV-visible spectrum of the films were examined. In the course of UV irradiation, the absorbance at 280 nm was reduced. Fibroblast cells were cultured on the photocrosslinked HPC-C films, and cell growth was examined. The cell proliferation test revealed that the photocrosslinked HPC-C films have good compatibility with fibroblast cells.

肉桂酰基修饰的碳水化合物材料的生物相容性不是众所周知的，尽管它们作为光反应性材料引起了人们的注意。为了研究肉桂酰基修饰的碳水化合物的生物相容性，将羟丙基纤维素（HPC）与肉桂酰基氯反应以产生肉桂酰基修饰的HPC（HPC-C），用于细胞增殖测试。通过改变肉桂酰氯与HPC的进料比，可以制备具有三种不同取代度（DS）的HPC-C。每1个羟丙基脱水葡萄糖单位的产品的DS为1.3-3.0。使用DSC和TGA进行的热分析表明，具有较高DS的HPC-C具有玻璃化转变温度和较高的热稳定性。在HPC-C薄膜上照射紫外线（UV），并检查薄膜的UV-可见光谱变化。在紫外线照射过程中，在280 nm处的吸光度降低。在光交联的HPC-C膜上培养成纤维细胞，并检查细胞的生长。细胞增殖测试表明，光交联的HPC-C膜与成纤维细胞具有良好的相容性。