Herein, we demonstrate the efficiency of NbCl₅ to promote a multicomponent reaction (MCR) for the synthesis of a library of phthalonitrile-quinoline dyads, which are very useful and new functionalized building blocks for phthalocyanine (PC) synthesis. Experimental mechanistic insights on the key MCR process are described, using a deuterated reagent, clearly showing the pericyclic nature of a hetero-Diels-Alder reaction. Examples of phthalocyanine (PC) syntheses were performed in order to demonstrate the versatility of the phthalonitrile-quinoline dyads. Preliminary photophysical measurements show that our phthalonitrile library is very promising for the production of new molecular scaffolds of PC derivatives with potential applications.

在这里，我们证明了NbCl ₅可以促进多组分反应（MCR）合成邻苯二甲腈-喹啉二元化合物的库，这对于酞菁（PC）合成是非常有用的和新的功能化构建基块。使用氘化试剂描述了关键MCR过程的实验机理，清楚地表明了杂Diels-Alder反应的周环性质。进行酞菁（PC）合成的示例，以证明邻苯二甲腈-喹啉二元化合物的多功能性。初步的光物理测量表明，我们的邻苯二甲腈文库对于具有潜在应用的PC衍生物新分子支架的生产非常有前途。