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Can innate immune system targets turn up the heat on 'cold' tumours?
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-12-28 , DOI: 10.1038/nrd.2017.264
Asher Mullard

Can innate immune system targets turn up the heat on 'cold' tumours?

Can innate immune system targets turn up the heat on 'cold' tumours?, Published online: 28 December 2018; doi:10.1038/nrd.2017.264

STING, RIG-I and NLRP3 agonists might increase the effectiveness of immuno-oncology checkpoint inhibitors, while antagonists of these targets offer an anti-inflammatory bonus.


中文翻译:

先天性免疫系统靶点能否提高“冷”肿瘤的热量?

先天性免疫系统靶点能否提高“冷”肿瘤的热量?

先天性免疫系统靶点能否提高``冷''肿瘤的发热量?在线发表于:2018年12月28日; doi:10.1038 / nrd.2017.264

STING,RIG-1和NLRP3激动剂可能会提高免疫肿瘤检查点抑制剂的效力,而这些靶点的拮抗剂可提供抗炎作用。
更新日期:2017-12-31
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