Challenging alkenes: The synthesis of the aglycon of disciformycin, a new secondary metabolite from Pyxidicoccus fallax, with high antibacterial potency is reported. The stereocontrolled installation of the olefinic double bonds at C2–C3/C3–C4 and C12–C13, respectively, as well the orthogonal differentiation of the oxy functionalities unexpectedly were found to be key challenges of the project.

中文翻译：

---

抗生素碟形霉素的糖苷配基的合成

具有挑战性的烯烃：据报道，合成了盘形霉素的糖苷配基，它是一种新的次生代谢产物，来自Pyxidicoccus fallax，具有很高的抗菌效力。立体控制的烯烃双键分别在C2-C3 / C3-C4和C12-C13的安装以及氧官能团的正交区分出乎意料地成为该项目的主要挑战。