Recent Advances in Extrusion‐Based 3D Printing for Biomedical Applications,Advanced Healthcare Materials

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Recent Advances in Extrusion‐Based 3D Printing for Biomedical Applications
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2017-12-28 , DOI: 10.1002/adhm.201701161
Jesse K Placone ₁ , Adam J Engler ₁

Affiliation

Additive manufacturing, or 3D printing, has become significantly more commonplace in tissue engineering over the past decade, as a variety of new printing materials have been developed. In extrusion‐based printing, materials are used for applications that range from cell free printing to cell‐laden bioinks that mimic natural tissues. Beyond single tissue applications, multi‐material extrusion based printing has recently been developed to manufacture scaffolds that mimic tissue interfaces. Despite these advances, some material limitations prevent wider adoption of the extrusion‐based 3D printers currently available. This progress report provides an overview of this commonly used printing strategy, as well as insight into how this technique can be improved. As such, it is hoped that the prospective report guides the inclusion of more rigorous material characterization prior to printing, thereby facilitating cross‐platform utilization and reproducibility.

中文翻译：

基于挤压的 3D 打印在生物医学应用中的最新进展

过去十年，随着各种新型打印材料的开发，增材制造（或 3D 打印）在组织工程中变得更加普遍。在基于挤出的打印中，材料的应用范围从无细胞打印到模仿自然组织的充满细胞的生物墨水。除了单一组织应用之外，最近还开发了基于多材料挤出的打印来制造模仿组织界面的支架。尽管取得了这些进步，但一些材料限制阻碍了目前可用的基于挤出的 3D 打印机的更广泛采用。本进度报告概述了这种常用的打印策略，并深入了解了如何改进该技术。因此，希望前瞻性报告能够指导在打印之前纳入更严格的材料表征，从而促进跨平台利用和可重复性。

更新日期：2017-12-28

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