Royal jelly is a functional food with several health promoting properties. The aim of present meta-analysis was to examine the role of royal jelly in blood lipid profiles. We systemically searched PUBMED, the Cochrane Library, Scopus, Web of Science and Google Scholar to identify eligible studies up to July 2017. Clinical trials which investigated the efficacy of royal jelly on adult blood lipid parameters were included. A random effects model was used for quantitative data synthesis. The pooled analysis of six trials suggested that royal jelly reduces total cholesterol blood levels. No significant change was observed in triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol blood concentrations. Subgroup analysis revealed a greater impact of RJ on the decrease of Total cholesterol and the increase of high-density lipoprotein cholesterol levels in studies with a long-term follow-up (≥90). This meta-analysis suggested that Royal jelly consumption might effective on improvement of lipid parameters.

蜂王浆是一种具有多种健康促进功能的功能性食品。本荟萃分析的目的是研究蜂王浆在血脂水平中的作用。我们系统搜索了PUBMED，Cochrane图书馆，Scopus，Web of Science和Google Scholar，以鉴定截至2017年7月的合格研究。其中包括调查蜂王浆对成人血脂参数功效的临床试验。随机效应模型用于定量数据合成。对六项试验的汇总分析表明，蜂王浆可降低总胆固醇血液水平。甘油三酸酯，低密度脂蛋白胆固醇和高密度脂蛋白胆固醇血药浓度均未见明显变化。亚组分析显示，在长期随访研究中（≥90），RJ对总胆固醇降低和高密度脂蛋白胆固醇水平升高的影响更大。这项荟萃分析表明食用蜂王浆可能对改善血脂参数有效。