A synthetic approach toward the phostriecin, an antitumor natural product is described. The key features of the present synthesis are Wittig reaction, synthesis of homoallylic alcohol using Brown’s protocol (alkoxyallylboration) and RCM for the creation of unsaturated lactone moiety of phostriecin.

中文翻译：

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全合成鬼臼苦素的研究

描述了一种抗幽门螺杆菌素（一种抗肿瘤天然产物）的合成方法。本合成的关键特征是维蒂希反应，使用布朗氏方法（烷氧基烯丙基化）合成均烯丙基醇和RCM以产生鬼臼素的不饱和内酯部分。