Hydrotalcite-derived (HT-derived) oxide catalysts were synthesised from hydrotalcite-like (HT-like) materials prepared by co-precipitation method (Cu-Al, Cu-Fe, Mg-Al, Mg-Fe, Ni-Fe and Ni-Al) followed by calcination and their catalytic activity was studied for oxidative amidation of carboxylic acids and substituted benzaldehydes with N,N-dimethylformamide (DMF). Catalyst screening was done using benzoic acid and DMF as a model reaction. Subsequently, we have optimised the reaction with different reaction parameters, catalyst loading, temperatures and oxidants. Cu-Fe HT-derived oxide catalyst showed excellent activity towards oxidative amidation using TBHP as an oxidant at 80 °C in 10 h. The fresh and spent catalysts were thoroughly characterised by different analytical techniques; XRD, SEM, HRTEM, TPD, N₂ adsorption-desorption isotherm and XPS. Moreover, the catalyst was easily separated by simple filtration and reused up to four cycles without significant loss in catalytic activity.

由共沉淀法制备的类水滑石（HT类）材料合成了水滑石类（HT类）氧化物催化剂（Cu-Al，Cu-Fe，Mg-Al，Mg-Fe，Ni-Fe和Ni -Al），然后煅烧，并研究了它们的催化活性对羧酸和取代的苯甲醛与N，N-二甲基甲酰胺（DMF）的氧化酰胺化作用。使用苯甲酸和DMF作为模型反应进行催化剂筛选。随后，我们用不同的反应参数，催化剂负载量，温度和氧化剂优化了反应。Cu-Fe HT衍生的氧化物催化剂在TBHP作为氧化剂于80°C的条件下在10小时内表现出优异的氧化酰胺化活性。用不同的分析技术对新鲜的和用过的催化剂进行了彻底的表征。XRD，SEM，HRTEM，TPD，N₂吸附-解吸等温线和XPS。而且，该催化剂易于通过简单的过滤进行分离，并且可以重复使用多达四个循环而不会显着降低催化活性。