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Curcumin - A promising nutritional strategy for chronic kidney disease patients
Journal of Functional Foods ( IF 3.8 ) Pub Date : 2017-12-22 , DOI: 10.1016/j.jff.2017.12.015
Livia de Almeida Alvarenga , Viviane de Oliveira Leal , Natália Alvarenga Borges , Aline Silva de Aguiar , Gerd Faxén-Irving , Peter Stenvinkel , Bengt Lindholm , Denise Mafra

Many studies have been conducted to identify therapeutic strategies to modulate inflammation and oxidative stress, complications that contribute to the increased morbidity and cardiovascular mortality in patients with chronic kidney disease (CKD). Among several non-pharmacological strategies, the use of bioactive compounds has emerged as a potential approach to reduce these complications in CKD patients. In this context, turmeric/curcumin may have positive consequences in terms of cardiovascular and nephroprotection because of its antibacterial, antiviral, anti-inflammatory and anti-oxidative effects. The aim of this review is to discuss the role of curcumin as a nutritional strategy to reduce cardiovascular risk factors as inflammation and oxidative stress in CKD patients.



中文翻译:

姜黄素-慢性肾脏病患者的一种有前景的营养策略

已经进行了许多研究来确定调节炎症和氧化应激的治疗策略,这些并发症导致慢性肾脏病(CKD)患者的发病率和心血管死亡率增加。在几种非药理学策略中,使用生物活性化合物已成为减少CKD患者并发症的潜在方法。在这种情况下,姜黄/姜黄素因其抗菌,抗病毒,抗炎和抗氧化作用,可能在心血管和肾保护方面产生积极作用。这篇综述的目的是讨论姜黄素作为减少CKD患者心血管疾病危险因素(如炎症和氧化应激)的营养策略的作用。

更新日期:2017-12-22
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