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Terpenoids from the mushroom-associated fungus Montagnula donacina
Phytochemistry ( IF 3.2 ) Pub Date : 2018-03-01 , DOI: 10.1016/j.phytochem.2017.12.015
Zhen-Zhu Zhao , Kuan Zhao , He-Ping Chen , Xue Bai , Ling Zhang , Ji-Kai Liu

Molecular identification suggested an edible mushroom, which was previously named as Craterellus odoratus should be revised as Montagnula donacina. A chemical re-investigation of the culture broth of this fungus resulted in the isolation of four rare tetracyclic bergamotane-type sesquiterpenoids, namely donacinolides A and B, donacinoic acids A and B, and three cadinane-type ones, namely donacinols A-C and a meroterpenoid (Z)-4-hydroxy-3-(3-hydroxy-3-methylbut-1-en-1-yl)benzoic acid. Their structures were established via extensive spectroscopic methods, single crystal X-ray diffraction analysis, and computational methods. (Z)-4-Hydroxy-3-(3-hydroxy-3-methylbut-1-en-1-yl)benzoic acid showed antibacterial activity against Staphylococcus aureus.

中文翻译:

来自蘑菇相关真菌 Montagnula donacina 的萜类化合物

分子鉴定表明一种可食用的蘑菇,以前被命名为 Craterellus odoratus 应该修改为 Montagnula donacina。对该真菌培养液的化学重新研究导致分离出四种稀有的四环佛手柑类倍半萜类化合物,即多纳西内酯 A 和 B、多纳西诺酸 A 和 B,以及三种卡地烷类型的,即多纳西诺 AC 和一种类萜(Z)-4-羟基-3-(3-羟基-3-甲基丁-1-烯-1-基)苯甲酸。它们的结构是通过广泛的光谱方法、单晶 X 射线衍射分析和计算方法建立的。(Z)-4-Hydroxy-3-(3-hydroxy-3-methylbut-1-en-1-yl)benzoic acid 对金黄色葡萄球菌显示出抗菌活性。
更新日期:2018-03-01
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