Grapefruit (Citrus paradisi Mcfad) is a perenifolium tree 5–6 m high with a fruit of about 15 cm in diameter, protected by the peel we can find about 11–14 segments (carpels), each of which is surrounded by a membrane and each containing the juice sacs, as well as the seeds. The fruit is made up of numerous compounds, and is known to have nutritive value because of the presence of various vitamins and minerals, among other chemicals. The fruit is also used in the field of gastronomy. Information has been accumulated regarding the participation of the fruit structures in a variety of biomedical, antigenotoxic and chemopreventive effects, surely related with the presence of the numerous chemicals that have been determined to constitute the fruit. Such studies have been carried out in different in vitro and in vivo experimental models, and in a few human assays. The information published so far has shown interesting results, therefore, the aims of the present review are to initially examine the main characteristics of the fruit, followed by systematization of the acquired knowledge concerning the biomedical, antigenotoxic and chemopreventive effects produced by the three main structures of the fruit: peel, seed, and pulp.

葡萄柚（Citrus paradisi Mcfad）是一棵高5–6 m的百日草树，果实直径约15 cm，在果皮的保护下，我们可以发现约11–14个果皮（果皮），每个果皮都被膜包围，每个都包含汁囊和种子。水果由多种化合物组成，由于存在多种维生素和矿物质以及其他化学物质，因此具有营养价值。水果也用于美食领域。已经积累了有关水果结构参与各种生物医学，抗原毒性和化学预防作用的信息，这肯定与已确定构成水果的多种化学物质的存在有关。此类研究已在不同的体外和体内实验模型以及一些人类试验。迄今为止发表的信息显示出有趣的结果，因此，本综述的目的是首先检查水果的主要特征，然后将所获得的有关三种主要结构产生的生物医学，抗原毒性和化学预防作用的知识系统化水果：果皮，种子和果肉。